兔抗CCND1(Phospho-Ser90)多克隆抗体

Background:

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition.

Applications:

WB

Name of antibody:

CCND1(Phospho-Ser90)

Immunogen:

Peptide sequence around phosphorylation site of serine 90(F-L-S(p)-L-E) derived from Human Cyclin D1 .

Full name:

cyclin D1

Synonyms：

BCL1; PRAD1; U21B31; D11S287E

SwissProt:

P24385

WB Predicted band size:

34 kDa

WB Positive control:

K562 cells lysates

WB Recommended dilution:

500-1000