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Background: |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
IL1A |
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Immunogen: |
Fusion protein of human IL1A |
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Full name: |
interleukin 1, alpha |
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Synonyms： |
IL1; IL-1A; IL1F1; IL1-ALPHA |
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SwissProt: |
P01583 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and human liver cancer |
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IHC Recommend dilution: |
50-200 |
