小鼠抗NFKBIA(N-term)单克隆抗体

Background:

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Applications:

WB

Name of antibody:

NFKBIA(N-term)

Immunogen:

Fusion protein of human NFKBIA

Full name:

NFKB inhibitor alpha

Synonyms:

IKBA; MAD-3; NFKBI

SwissProt:

P25963

WB Predicted band size:

36 kDa

WB Positive control:

Jurkat and Hela cell lysates

WB Recommended dilution:

1000-5000