购物车
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021-54845833/15800441009
别 名： integrin subunit alpha V; CD51; MSK8; VNRA; VTNR
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Background: |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ITGAV |
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Immunogen: |
Synthetic peptide of human ITGAV |
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Full name: |
integrin subunit alpha V |
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Synonyms: |
CD51; MSK8; VNRA; VTNR |
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SwissProt: |
P06756 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
50-100 |
