小鼠抗ARL2BP单克隆抗体

Background:

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC

Name of antibody:

ARL2BP

Immunogen:

Fusion protein of human ARL2BP

Full name:

ADP-ribosylation factor-like 2 binding protein (ARL2BP)

Synonyms:

BART; BART1; RP66

SwissProt:

Q9Y2Y0

IHC positive control:

human colon tissue and carcinoma of human kidney tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

19 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK cell lysates

WB Recommended dilution:

1000-5000