小鼠抗PPT1单克隆抗体

Background:

The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008].

Applications:

WB, IHC

Name of antibody:

PPT1

Immunogen:

Fusion protein of human PPT1

Full name:

palmitoyl-protein thioesterase 1 (PPT1), transcript variant 1

Synonyms:

CLN1; INCL; PPT

SwissProt:

P50897

IHC positive control:

carcinoma of human prostate tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

34 kDa

WB Positive control:

HepG2, Hela, A549, COS7, Jurkat, MDCK, MCF-7 cell lysates

WB Recommended dilution:

1000-5000