兔抗PPARG多克隆抗体

Background:

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

PPARG

Immunogen:

Synthetic peptide of human PPARG

Full name:

peroxisome proliferator activated receptor gamma

Synonyms:

GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma

SwissProt:

P37231

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human breast cancer

IHC Recommend dilution:

20-100