兔抗DSG1多克隆抗体

Background:

Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.

Applications:

ELISA, WB

Name of antibody:

DSG1

Immunogen:

Synthetic peptide of human DSG1

Full name:

desmoglein 1

Synonyms：

DG1; DSG; CDHF4; PPKS1; SPPK1

SwissProt:

Q02413

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

114 kDa

WB Positive control:

Human tongue cancer tissue

WB Recommended dilution:

200-1000