兔抗Fadd(Ab-191) 多克隆抗体

Background:

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis By similarity. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling By similarity.

Applications:

WB

Name of antibody:

Fadd(Ab-191)

Immunogen:

Synthesized peptide derived from C-terminal of human FADD.

Full name:

Fas (TNFRSF6)-associated via death domain

Synonyms：

GIG3; MORT1

SwissProt:

Q61160/Q13158

WB Predicted band size:

23 kDa

WB Positive control:

A549 cells lysates

WB Recommended dilution:

500-3000