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021-54845833/15800441009
中文名称： 兔抗CR1多克隆抗体
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Background: |
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CR1 |
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Immunogen: |
Synthetic peptide of human CR1 |
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Full name: |
complement component (3b/4b) receptor 1 (Knops blood group) |
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Synonyms： |
KN; C3BR; C4BR; CD35 |
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SwissProt: |
P17927 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
