兔抗UBE2D2多克隆抗体

Background:

Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.

Applications:

WB

Name of antibody:

UBE2D2

Immunogen:

Synthesized peptide derived from C-terminal of human UBE2D2.

Full name:

ubiquitin-conjugating enzyme E2D 2

Synonyms：

UBC4; PUBC1; UBCH4; UBC4/5; UBCH5B; E2(17)KB2

SwissProt:

P62837

WB Predicted band size:

17 kDa

WB Positive control:

Hela cells, A549 cells and K562 cells lysates

WB Recommended dilution:

500-3000