小鼠抗RNF4单克隆抗体

Background:

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.

Applications:

WB

Name of antibody:

RNF4

Immunogen:

Fusion protein of human RNF4

Full name:

ring finger protein 4

Synonyms:

SLX5; SNURF; RES4-26

SwissProt:

P78317

WB Predicted band size:

21 KD

WB Positive control:

Hela, MCF7, PC-12 cell lysates

WB Recommended dilution:

500-2000