欢迎来到上海通蔚!

021-54845833/15800441009

品质保证 · 通蔚试剂

当前位置: 首页 > 科研产品 > 科研抗体 > 一抗 > 兔抗PHAX多克隆抗体
  • 兔抗PHAX多克隆抗体

    规格:
    数量:

    购买数量

    价格:
    • 品牌 : 通蔚生物
    • 目录号 : TW21605
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存:80
  • 商品详情
  • 参考文献
  • 说明书下载
  • 商品评论0
  • 相关产品

中文名称: 兔抗PHAX多克隆抗体


英文名称: Anti-PHAX rabbit polyclonal antibody


别       名: RNUXA


相关类别: 一抗


储      存: 冷冻(-20℃) 避光


宿      主: Rabbit


抗      原: PHAX


反应种属: Human


标  记  物: Unconjugate


克隆类型: rabbit polyclonal


技术规格

WB Recommended dilution:

500-3000

WB Positive control:

HT-29 cells lysate

WB Predicted band size:

44 kDa

SwissProt:

Q9H814

Synonyms:

RNUXA

Full name:

phosphorylated adaptor for RNA export

Immunogen:

Synthesized peptide derived from internal of human RNUXA.

Name of antibody:

PHAX

Applications:

WB

Background:

A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner By similarity. Plays also a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA.