兔抗UGT1A6多克隆抗体

Background:

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

Applications:

ELISA, IHC

Name of antibody:

UGT1A6

Immunogen:

Synthetic peptide of humanUGT1A6

Full name:

UDP glucuronosyltransferase 1 family, polypeptide A6

Synonyms：

GNT1; UGT1; HLUGP; UDPGT; UGT1F; HLUGP1; UGT1A6S; UDPGT 1-6

SwissProt:

P19224

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human thyroid cancer

IHC Recommend dilution:

25-100