兔抗ABCB8多克隆抗体

Background:

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.

Applications:

ELISA, WB

Name of antibody:

ABCB8

Immunogen:

Fusion protein of human ABCB8

Full name:

ATP-binding cassette sub-family B member 8

Synonyms：

MABC1, M-ABC1, EST328128

SwissProt:

Q9NUT2

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

80 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

500-2000