兔抗ACOT8多克隆抗体

Background:

The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes.

Applications:

ELISA, IHC

Name of antibody:

ACOT8

Immunogen:

Fusion protein of human ACOT8

Full name:

acyl-CoA thioesterase 8

Synonyms：

hTE; PTE1; PTE2; PTE-1; PTE-2; HNAACTE; hACTE-III

SwissProt:

O14734

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human cervical cancer and human thyroid cancer

IHC Recommend dilution:

15-50