兔抗CCDC102B多克隆抗体

Background:

CCDC102B (coiled-coil domain containing 102B), also known as AN, ACY1L or HsT1731, is a 513 amino acid protein that exists as three alternatively spliced isoforms. Widely expressed and found in multiple CNV (copy-number variant) regions, CCDC102B contains the deletion breakpoint of a maternally inherited deletion, which is 2.7?Mb in size, and maps to human chromosome 18q22.1. CCDC102B may play a role in the pathogenesis of diaphragmatic hernia, microphthalmia, colorectal carcinoma and schizophrenia. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Translocation between chromosomes 18 and 14 is the most common translocation in cancers and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18.

Applications:

ELISA, WB

Name of antibody:

CCDC102B

Immunogen:

Full length fusion protein

Full name:

coiled-coil domain containing 102B

Synonyms:

AN; ACY1L; HsT1731; C18orf14

SwissProt:

Q68D86

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

60 kDa

WB Positive control:

HEPG2, HUVEC and PC-3 cell lysates

WB Recommended dilution:

200-1000