兔抗CDH10多克隆抗体

Background:

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

Applications:

IF

Name of antibody:

CDH10

Immunogen:

Synthesized peptide derived from internal of human CDH10.

Full name:

cadherin 10, type 2 (T2-cadherin)

Synonyms：

0

SwissProt:

Q9Y6N8

IF positive control:

LOVO cells

IF Recommend dilution:

100-500