小鼠抗RPL10A单克隆抗体

Background:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Applications:

WB, IHC

Name of antibody:

RPL10A

Immunogen:

Fusion protein of human RPL10A

Full name:

ribosomal protein L10a

Synonyms:

L10A; CSA19; NEDD6; Csa-19

SwissProt:

P62906

IHC positive control:

Human lymphoma tissue and Human lung cancer

IHC Recommend dilution:

500-2000

WB Predicted band size:

25 KD

WB Positive control:

HepG2, PC12, Jurkat and Hela cell lysates

WB Recommended dilution:

500-2000