小鼠抗RAB30单克隆抗体

Background:

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins.

Applications:

WB, IHC, IF

Name of antibody:

RAB30

Immunogen:

Fusion protein of human RAB30

Full name:

RAB30, member RAS oncogene family (RAB30), transcript variant 2

Synonyms:

RAB30, member RAS oncogene family

SwissProt:

Q15771

IHC positive control:

human pancreas tissue and carcinoma of human thyroid tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

23 kDa

WB Positive control:

SVT2, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

200-1000