兔抗CLPS多克隆抗体

Background:

The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

CLPS

Immunogen:

Fusion protein of human CLPS

Full name:

colipase, pancreatic

SwissProt:

P04118

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and Human gastric cancer

IHC Recommend dilution:

50-200