小鼠抗PRMT5单克隆抗体

Background:

This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

WB

Name of antibody:

PRMT5

Immunogen:

Fusion protein of human PRMT5

Full name:

protein arginine methyltransferase 5

Synonyms:

JBP1; SKB1; IBP72; SKB1Hs; HRMT1L5

SwissProt:

O14744

WB Predicted band size:

73 KD

WB Positive control:

K562 cell lysate

WB Recommended dilution:

200-1000