兔抗DNTT多克隆抗体

Background:

This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Applications:

ELISA, IHC

Name of antibody:

DNTT

Immunogen:

Fusion protein of human DNTT

Full name:

DNA nucleotidylexotransferase

Synonyms:

TDT

SwissProt:

P04053

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

20-100