| Background: | This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. | 
| Applications: | ELISA, IHC | 
| Name of antibody: | DNTT | 
| Immunogen: | Fusion protein of human DNTT | 
| Full name: | DNA nucleotidylexotransferase | 
| Synonyms: | TDT | 
| SwissProt: | P04053 | 
| ELISA Recommended dilution: | 5000-10000 | 
| IHC positive control: | Human esophagus cancer | 
| IHC Recommend dilution: | 20-100 | 
	
	 
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