兔抗DDX43多克隆抗体

Background:

DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43), also known as CT13 or HAGE, is a 648 amino acid protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis.

Applications:

ELISA, WB, IHC

Name of antibody:

DDX43

Immunogen:

Fusion protein of human DDX43

Full name:

DEAD (Asp-Glu-Ala-Asp) box polypeptide 43

Synonyms：

CT13; HAGE

SwissProt:

Q9NXZ2

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

73 kDa

WB Positive control:

HepG2 cells

WB Recommended dilution:

200-1000