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中文名称：小鼠抗AKAP12单克隆抗体
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Background: |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
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Applications: |
WB, IHC |
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Name of antibody: |
AKAP12 |
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Immunogen: |
Fusion protein of human AKAP12 |
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Full name: |
A-kinase anchoring protein 12 |
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Synonyms: |
SSeCKS; AKAP250 |
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SwissProt: |
Q02952 |
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IHC positive control: |
Human spleen tissue and Human testicle tissue; Human adult heart tissue |
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IHC Recommend dilution: |
200-500 |
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WB Predicted band size: |
191 KD |
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WB Positive control: |
U251 and Hela cell lysates |
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WB Recommended dilution: |
500-2000 |
