兔抗KDM2B多克隆抗体

Background:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Applications:

ELISA, IHC

Name of antibody:

KDM2B

Immunogen:

Synthetic peptide of human KDM2B

Full name:

lysine demethylase 2B

Synonyms:

CXXC2; Fbl10; PCCX2; FBXL10; JHDM1B

SwissProt:

Q8NHM5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human breast cancer and Human brain

IHC Recommend dilution:

50-200