兔抗HK1/HK2多克隆抗体

Background:

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Applications:

ELISA, IHC

Name of antibody:

HK1/HK2

Immunogen:

Fusion protein of human HK1/HK2

Full name:

hexokinase 1/2

Synonyms:

HK; HKD; HKI; HXK1; RP79; HMSNR; HK1-ta; HK1-tb; HK1-tc; hexokinase; HKII; HXK2

SwissProt:

P19367/P52789

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human brain and Human thyroid cancer

IHC Recommend dilution:

50-200