兔抗LRRC23多克隆抗体

Background:

The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic /∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeasts and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.

Applications:

ELISA, IHC

Name of antibody:

LRRC23

Immunogen:

Synthetic peptide of human LRRC23

Full name:

leucine rich repeat containing 23

Synonyms:

LRPB7

SwissProt:

Q53EV4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human esophagus cancer

IHC Recommend dilution:

25-100