兔抗ABHD12多克隆抗体

Background:

This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Applications:

ELISA, IHC

Name of antibody:

ABHD12

Immunogen:

Fusion protein of human ABHD12

Full name:

abhydrolase domain containing 12

Synonyms：

PHARC; ABHD12A; BEM46L2; C20orf22; dJ965G21.2

SwissProt:

Q8N2K0

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

25-100