小鼠抗PTF1A单克隆抗体

Background:

This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

Applications:

WB

Name of antibody:

PTF1A

Immunogen:

Fusion protein of human PTF1A

Full name:

pancreas specific transcription factor, 1a

Synonyms:

PACA; PAGEN2; bHLHa29; PTF1-p48

SwissProt:

Q7RTS3

WB Predicted band size:

35 KD

WB Positive control:

Mouse brain tissue, Rat brain tissue lysates

WB Recommended dilution:

200-1000