购物车
帮助
021-54845833/15800441009
|
Background: |
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
|
Applications: |
WB, IHC |
|
Name of antibody: |
GAB2(Ab-159) |
|
Immunogen: |
Synthesized non-phosphopeptide derived from human GRB2 around the phosphorylation site of serine 159 (K-S-S(p)-A-P). |
|
Full name: |
GRB2-associated binding protein 2 |
|
Synonyms： |
KIAA0571 |
|
SwissProt: |
Q9UQC2 |
|
IHC positive control: |
Human colon carcinoma tissue |
|
IHC Recommend dilution: |
50-100 |
|
WB Predicted band size: |
74 kDa |
|
WB Positive control: |
COS cells lysate |
|
WB Recommended dilution: |
500-3000 |
