兔抗APLP1多克隆抗体

Background:

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

APLP1

Immunogen:

Fusion protein of human APLP1

Full name:

Amyloid beta (A4) precursor-like protein 1

Synonyms：

APLP

SwissProt:

P51693

ELISA Recommended dilution:

500-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

72 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

500-2000