兔抗IRF8多克隆抗体

Background:

Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Applications:

ELISA, WB

Name of antibody:

IRF8

Immunogen:

Fusion protein of human IRF8

Full name:

interferon regulatory factor 8

Synonyms:

ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP

SwissProt:

Q02556

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

48 kDa

WB Positive control:

Raji cell lysate

WB Recommended dilution:

200-1000