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Background: |
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
EBI3 |
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Immunogen: |
Fusion protein of human EBI3 |
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Full name: |
Epstein-Barr virus induced 3 |
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Synonyms: |
IL27B; IL35B; IL-27B |
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SwissProt: |
Q14213 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
150-300 |
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WB Predicted band size: |
25 kDa |
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WB Positive control: |
Mouse kidney tissue, 293T cell lysates |
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WB Recommended dilution: |
500-2000 |
