兔抗CD68多克隆抗体

Background:

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

CD68

Immunogen:

Synthetic peptide of human CD68

Full name:

CD68 molecule

Synonyms：

GP110; LAMP4; SCARD1

SwissProt:

P34810

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and Human lung cancer

IHC Recommend dilution:

50-200