兔抗INSR多克隆抗体

Background:

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

INSR

Immunogen:

Synthetic peptide of human INSR

Full name:

insulin receptor

Synonyms:

HHF5; CD220

SwissProt:

P06213

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human esophagus cancer

IHC Recommend dilution:

20-100