兔抗BAIAP2多克隆抗体

Background:

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms

Applications:

ELISA, IHC

Name of antibody:

BAIAP2

Immunogen:

Fusion protein of human BAIAP2

Full name:

BAI1-associated protein 2

Synonyms：

BAP2, FLAF3, IRSP53

SwissProt:

Q9UQB8

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer

IHC Recommend dilution:

50-200