兔抗INS(C-peptide)多克隆抗体

Background:

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

INS(C-peptide)

Immunogen:

Synthetic peptide of human INS(C-peptide)

Full name:

insulin

Synonyms:

IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10

SwissProt:

P01308

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human liver cancer

IHC Recommend dilution:

25-50