兔抗MSH3多克隆抗体

Background:

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.

Applications:

ELISA, WB, IHC

Name of antibody:

MSH3

Immunogen:

Fusion protein of human MSH3

Full name:

mutS homolog 3

Synonyms:

DUP; FAP4; MRP1

SwissProt:

P20585

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and Human esophagus cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

127 kDa

WB Positive control:

Jurkat cell lysate

WB Recommended dilution:

500-2000