兔抗NECAB3多克隆抗体

Background:

he protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB, IF

Name of antibody:

NECAB3

Immunogen:

Synthesized peptide derived from internal of human NECAB3.

Full name:

N-terminal EF-hand calcium binding protein 3

Synonyms：

NIP1; XB51; STIP3; EFCBP3; SYTIP2; APBA2BP; dJ63M2.4; dJ63M2.5

SwissProt:

Q96P71

WB Predicted band size:

44 kDa

WB Positive control:

COLO cells, HepG2 cells and HT-29 cells lysates

WB Recommended dilution:

500-3000

IF positive control:

A549 cells

IF Recommend dilution:

100-500