小鼠抗CBX8单克隆抗体

Background:

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Applications:

WB, IHC

Name of antibody:

CBX8

Immunogen:

Fusion protein of human CBX8

Full name:

chromobox homolog 8 (CBX8)

Synonyms:

PC3; RC1

SwissProt:

Q9HC52

IHC positive control:

carcinoma of human thyroid tissue

IHC Recommend dilution:

25-100

WB Predicted band size:

43 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

1000-5000