小鼠抗DDX58单克隆抗体

Background:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC, IF

Name of antibody:

DDX58

Immunogen:

Fusion protein of human DDX58

Full name:

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (DDX58)

Synonyms:

RIGI; RIG-I; RLR-1; SGMRT2

SwissProt:

O95786

IHC positive control:

adenocarcinoma of human ovary tissue and human pancreas tissue; adenocarcinoma of human breast tissue and human liver tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

107 kDa

WB Positive control:

COS7 cell lysate

WB Recommended dilution:

200-1000