兔抗IHO1多克隆抗体

Background:

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

Applications:

ELISA, IHC

Name of antibody:

IHO1

Immunogen:

Fusion protein of human IHO1

Full name:

interactor of HORMAD1 1

Synonyms:

CT74; LELA1; CCDC36

SwissProt:

Q8IYA8

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

100-300