宿 主: Rabbit
| Background: | Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. | 
| Applications: | WB, IHC | 
| Name of antibody: | ITGB4(Ab-1510) | 
| Immunogen: | Synthesized non-phosphopeptide derived from human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-Y(p)-S-T). | 
| Full name: | integrin, beta 4 | 
| Synonyms: | CD104 | 
| SwissProt: | P16144 | 
| IHC positive control: | Human breast carcinoma tissue | 
| IHC Recommend dilution: | 50-100 | 
| WB Predicted band size: | 202 kDa | 
| WB Positive control: | HepG2 cells treated with PMA (125ng/ml, 30mins) lysate | 
| WB Recommended dilution: | 500-3000 | 

		

	
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