兔抗HNRNPH2多克隆抗体

Background:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.

Applications:

ELISA, WB, IHC

Name of antibody:

HNRNPH2

Immunogen:

Fusion protein of human HNRNPH2

Full name:

heterogeneous nuclear ribonucleoprotein H2 (H')

Synonyms:

FTP3; HNRPH'; HNRPH2; hnRNPH'

SwissProt:

P55795

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

49 kDa

WB Positive control:

293T，231 and K562 cell lysates

WB Recommended dilution:

200-1000