小鼠抗FSCN1单克隆抗体

Background:

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Applications:

ELISA, WB

Name of antibody:

FSCN1

Immunogen:

Fusion protein of human FSCN1

Full name:

fascin actin-bundling protein 1

Synonyms:

HSN; SNL; p55; FAN1

SwissProt:

Q16658

WB Predicted band size:

55 kDa

WB Positive control:

HEPG2 whole cell lysate

WB Recommended dilution:

500-2000