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Background: |
This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DNA2 |
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Immunogen: |
Fusion protein of human DNA2 |
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Full name: |
DNA replication helicase/nuclease 2 |
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Synonyms: |
DNA2L; hDNA2 |
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SwissProt: |
P51530 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human breast cancer |
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IHC Recommend dilution: |
50-100 |
