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中文名称：兔抗GRIN2B(Ab-1303) 多克隆抗体
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Background: |
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death By similarity. |
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Applications: |
WB |
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Name of antibody: |
GRIN2B(Ab-1303) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human GRIN2B around the phosphorylation site of serine 1303 (Q-H-S(p)-Y-D). |
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Full name: |
glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
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Synonyms： |
MRD6; NR2B; hNR3; GluN2B; NMDAR2B |
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SwissProt: |
Q13224 |
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WB Predicted band size: |
166 kDa |
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WB Positive control: |
NIH/3T3 cells lysates |
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WB Recommended dilution: |
500-3000 |
