兔抗CHRNA4多克隆抗体

Background:

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.

Applications:

ELISA, IHC

Name of antibody:

CHRNA4

Immunogen:

Fusion protein of human CHRNA4

Full name:

cholinergic receptor, nicotinic, alpha 4 (neuronal)

Synonyms：

EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4

SwissProt:

P43681

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain

IHC Recommend dilution:

50-200