小鼠抗NFKBIA单克隆抗体

Background:

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011].

Applications:

WB, IF

Name of antibody:

NFKBIA

Immunogen:

Fusion protein of human NFKBIA

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA)

Synonyms:

IKBA; MAD-3; NFKBI

SwissProt:

P25963

WB Predicted band size:

36 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7 cell lysates

WB Recommended dilution:

500-2000